Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
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Case Report

Volume 14, Number 1, February 2025, pages 32-37

A Rare Case of Acute Aleukemic Mast Cell Leukemia With Osteoblastic Lesions in the Appendicular Skeleton

Figures

↓  Figure 1. CT chest with contrast showing the osteoblastic lesions in the ribs (a) and vertebrae (b) (arrows). CT: computed tomography.
Figure 1.
↓  Figure 2. CT abdomen and pelvis with contrast showing the pelvic osteoblastic lesions (arrows). CT: computed tomography.
Figure 2.
↓  Figure 3. CT abdomen and pelvis with contrast showing hepatosplenomegaly and dilated portal vein (arrows). CT: computed tomography.
Figure 3.
↓  Figure 4. Bone marrow biopsy showing atypical mast cells (arrows).
Figure 4.
↓  Figure 5. Bone marrow biopsy showing cells with CD117 expression.
Figure 5.
↓  Figure 6. Left ilium bone biopsy showing atypical mast cells.
Figure 6.
↓  Figure 7. Left ilium bone biopsy showing cells with CD117 expression.
Figure 7.

Table

↓  Table 1. Pertinent Laboratory Results on Presentation
 
Laboratory test Day 1 Reference range
AST: aspartate aminotransferase; ALT: alanine aminotransferase; BUN: blood urea nitrogen.
White blood count (WBC) 3.3 4 - 11 × 103/µL
Hemoglobin 11.3 12 - 16 g/dL
Hematocrit 32 36-48%
Platelet 104 150 - 450 × 103/µL
Alkaline phosphatase 362 40 - 129 U/L
Total bilirubin 2 0.0 - 1.0 mg/dL
AST/ALT 38/23 10 - 40 U/L
Potassium 2.5 3.5 - 5 mmol/L
BUN 12 8 - 23 mg/dL
Creatinine 0.57 0.5 - 1.0 mg/dL
Total protein 5.9 6.0 - 8.3 gm/dL
Albumin 3.1 3.5 - 5.2 gm/dL
Calcium 8.6 8.5 - 10.2 mg/dL