| Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
| Journal website https://jh.elmerpub.com |
Case Report
Volume 13, Number 6, December 2024, pages 285-289
Sequential Use of Prednisolone and Cyclosporine Is Effective in the Management of Immunotherapy-Related Hemolytic Anemia
Tables
| March 23, 2023 | April 13, 2023 | |
|---|---|---|
| Complete blood count | ||
| Hemoglobin | 11 | 11.8 |
| White blood cells | 3.30 | 7.08 |
| Platelets | 275 | 194 |
| Metabolic profile | ||
| Creatinine | 0.51 | 0.55 |
| Total bilirubin | 0.17 | 0.17 |
| Treatment days | Hb range | Total PRBCs | Prednisolone | Cyclosporine |
|---|---|---|---|---|
| Hb: hemoglobin; PRBCs: packed red blood cells. | ||||
| D1 - 7 | 3.9 - 5.7 | 7 | None | None |
| D8 - 14 | 5.5 - 8.2 | 7 | 100 mg | None |
| D15 - 21 | 5.3 - 6.5 | 3 | 100 mg | None |
| D22 - 28 | 5.8 - 6.6 | 1 | Steroid taper | 200 mg |
| Weeks 5 - 8 (month 2) | 11.8 - 12.3 | 0 | Steroid taper | 200 mg |
| Weeks 9 - 12 (month 3) | 12.5 - 13 | 0 | None | 100 mg |
| Weeks 13 - 16 (month 4) | 10.9 - 12.7 | 0 | None | 50 mg |
| Week | Haptoglobin | LDH | Bilirubin: total/direct |
|---|---|---|---|
| LDH: lactate dehydrogenase. | |||
| Week 1 | < 10 | 1,368 | 1.79/0.3 |
| Week 2 | < 10 | 2,334 | 2.30/0.5 |
| Week 3 | < 10 | 1,578 | 1.11/0.2 |
| Week 4 | < 10 | 1,048 | 0.89/0.2 |